A new pandemic

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   https://afludiary.blogspot.com/2025/05/preprint-progressive-adaptation-of-h6n1.html or https://afludiary.blogspot.com/2025/05/preprint-progressive-adaptation-of-h6n1.html ;the OIE (now WOAH) decided to make LPAI H5 and H7 viruses reportable in 2006, and infected captive birds subject to immediate eradication (see Terrestrial Animal Code Article 10.4.1.)
But as we've discussed often, there are other zoonotic or potentially zoonotic avian flu viruses (H3, H4, H6, H9, H10, etc.) which are not reportable, and are often tolerated or ignored because they produce relatively minor financial losses to the poultry industry.
LPAI H9N2, which is now rife in poultry in Asia, the Middle East, and increasingly in Africa, is perhaps the most obvious threat.  We've seen > 140 documented human infections
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Attempts to control H9N2 with vaccines in China over the past 30 years have been less than successful (see NPJ Vaccines: Impact of Inactivated Vaccine on Transmission and Evolution of H9N2 Avian Influenza Virus in Chickens), and the virus continues to evolve.     
But increasingly China has warned on the spread (in wild birds and poultry) and zoonotic potential of other LPAI viruses, including H3Nx, H4Nx, H6Nx, and H10Nx. 
If there is a common denominator among these varied LPAI viruses, it is that the longer they circulate in poultry, the greater the zoonotic threat they appear to pose. Their evolution may be far slower than H5 and H7 viruses, but that doesn't make them benign.  
Only easier to ignore.
Twelve years ago - during the opening salvo of H7N9's first wave in China - Taiwan reported the world's first known human infection with LPAI H6N1 (see Taiwan CDC: Epidemiological Analysis Of Human H6N1 Infection).  A year later, Taiwan reported an outbreak in dogs (see EID Journal: Influenza A(H6N1) In Dogs, Taiwan).
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But since LPAI H6 viruses only rarely produce clinical illness in poultry, and are not legally reportable to the OIE (now WOAH), we are only rarely made aware of their presence, or of the potential threat they may pose.

DJ, If politics decides solving problems is a waste of money (from the rich 0,1%) there is NO point in ANY science...

Pandemics, climate collapse continue to intermix and worsen the global crisis..."politics/oligarchy" going for war to benifit the 0,1%...

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Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Online Points: 1994	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 12 hours 23 minutes ago at 12:18am
	https://afludiary.blogspot.com/2025/05/preprint-progressive-adaptation-of-h6n1.html or https://afludiary.blogspot.com/2025/05/preprint-progressive-adaptation-of-h6n1.html ; the OIE (now WOAH) decided to make LPAI H5 and H7 viruses reportable in 2006, and infected captive birds subject to immediate eradication (see Terrestrial Animal Code Article 10.4.1.) But as we've discussed often, there are other zoonotic or potentially zoonotic avian flu viruses (H3, H4, H6, H9, H10, etc.) which are not reportable, and are often tolerated or ignored because they produce relatively minor financial losses to the poultry industry. LPAI H9N2, which is now rife in poultry in Asia, the Middle East, and increasingly in Africa, is perhaps the most obvious threat. We've seen > 140 documented human infections - Attempts to control H9N2 with vaccines in China over the past 30 years have been less than successful (see NPJ Vaccines: Impact of Inactivated Vaccine on Transmission and Evolution of H9N2 Avian Influenza Virus in Chickens), and the virus continues to evolve. But increasingly China has warned on the spread (in wild birds and poultry) and zoonotic potential of other LPAI viruses, including H3Nx, H4Nx, H6Nx, and H10Nx. If there is a common denominator among these varied LPAI viruses, it is that the longer they circulate in poultry, the greater the zoonotic threat they appear to pose. Their evolution may be far slower than H5 and H7 viruses, but that doesn't make them benign. Only easier to ignore. Twelve years ago - during the opening salvo of H7N9's first wave in China - Taiwan reported the world's first known human infection with LPAI H6N1 (see Taiwan CDC: Epidemiological Analysis Of Human H6N1 Infection). A year later, Taiwan reported an outbreak in dogs (see EID Journal: Influenza A(H6N1) In Dogs, Taiwan). - But since LPAI H6 viruses only rarely produce clinical illness in poultry, and are not legally reportable to the OIE (now WOAH), we are only rarely made aware of their presence, or of the potential threat they may pose. DJ, If politics decides solving problems is a waste of money (from the rich 0,1%) there is NO point in ANY science... Pandemics, climate collapse continue to intermix and worsen the global crisis..."politics/oligarchy" going for war to benifit the 0,1%...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Online Points: 1994	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 10 hours 60 minutes ago at 1:41am
	https://halturnerradioshow.com/index.php/news-selections/world-news/u-s-imposes-full-scale-secondary-sanctions-upon-iran-oil or https://halturnerradioshow.com/index.php/news-selections/world-news/u-s-imposes-full-scale-secondary-sanctions-upon-iran-oil ; UPDATE 2:10 AM EDT (FRIDAY) -- Just found out the real target is: China. China is the largest buyer of Iran oil, so it is China that is propping-up Iran economically. By issuing Secondary Sanctions, Trump is making it impossible for China to do __any__ business with the United States. Some people have speculated that Trump expected China to come to negotiate over Tariffs and the CLAIM is that China didn't even call. I am not certain that's true, because Chinese delegations were seen entering the US Treasury Department last week. They were photographed by someone outside and the Chinese DEMANDED the photos be deleted. They were not. There were several references by President Trump to China and the US "talking" which were all directly denied by China. Now I am learning that China has not negotiated and not even called the US about the Tariffs, but I cannot verify those claims. So these Secondary Sanctions issued by the US against Iran, seem to be trying to compel China to come to the negotiating table with the US under threat of not doing __any__ commerce with the USA, but this will backfire. About eighty percent (80%) of Pharmaceuticals in US Drug Stores are either made in China, or made in India but SOURCED from China. If the US were to cut-off all commerce with China (over Iran oil) then those medicines would not be shipped to the US - if they haven't stopped already. Can you imagine the level of trouble it would cause the US if 80% of its prescription medications stopped coming into the country? Not only would a whole slew of people die, the people who take Psych meds might all start flipping-out from suddenly being cut-off from them. It could be chaos. More if I get it. DJ, Why should China make ANY deals with trumpf ? The trumpf-junta does NOT care about climate or public health...maybe NGO's (Red Cross ?) can help Americans...the US oligarchy is KILLING its citizens...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Online Points: 1994	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 14 minutes ago at 12:27pm
	https://www.thailandmedical.news/news/breaking-the-new-sars-cov-2-variant-nb-1-8-1-is-the-most-dangerous-so-far-and-poses-a-major-threat or https://www.thailandmedical.news/news/breaking-the-new-sars-cov-2-variant-nb-1-8-1-is-the-most-dangerous-so-far-and-poses-a-major-threat The new NB.1.8.1 CoViD variant is not only better in evading immunity, better "fusogenity"= spreading from cell-to-cell, it is also binding to more receptors then ACE-2. Further links in the link-CoViD is NOT over... https://www.thailandmedical.news/news/new-sars-cov-2-variants-still-spread-through-the-air-but-each-has-a-unique-strategy-to-stay-contagious or https://www.thailandmedical.news/news/new-sars-cov-2-variants-still-spread-through-the-air-but-each-has-a-unique-strategy-to-stay-contagious link to https://www.nature.com/articles/s44298-025-00120-1 or https://www.nature.com/articles/s44298-025-00120-1 ; SARS-CoV-2 variants evolve to balance immune evasion and airborne transmission, yet the mechanisms remain unclear. In hamsters, first-wave, Alpha, and Delta variants transmitted efficiently via aerosols. Alpha emitted fewer viral particles than first-wave virus but compensated with a lower infectious dose (ID50). Delta exhibited higher airborne emission but required a higher ID50. A fall in airborne emission of infectious Delta virus over time after infection correlated with a decrease in its infectivity to RNA ratio in nasal wash and a decrease in contagiousness to sentinel animals. Omicron subvariants (BA.1, EG.5.1, BA.2.86, JN.1) displayed varying levels of airborne transmissibility, partially correlated with airborne emissions. Mutations in the non-spike genes contributed to reduced airborne transmissibility, since recombinant viruses with spike genes of BA.1 or JN.1 and non-spike genes from first-wave virus are more efficiently transmitted between hamsters. These findings reveal distinct viral strategies for maintaining airborne transmission. Early assessment of ID50 and aerosolized viral load may help predict transmissibility of emerging variants. DJ, Decrease of infectious virus particles may be compensated by an increase of viral particles-and the other way round...So virus mutations may not always alter how infections can spread via aerosols.