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Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus

A new pandemic

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Dutch Josh 2 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 4 hours 27 minutes ago at 2:03am
https://afludiary.blogspot.com/2025/04/two-surveys-uk-us-illustrating-publics.html or https://afludiary.blogspot.com/2025/04/two-surveys-uk-us-illustrating-publics.html ;

For those of us who loiter in the echo chamber of emerging infectious diseases, emergency preparedness, or who work in certain farming sectors, HPAI H5Nx is a legitimate public health concern; and while not guaranteed to spark the next pandemic, it is plausible contender. 

But for the vast majority of people - even those who watch the news or scroll social media - it is just one of hundreds of annoying threats they are incessantly bombarded with each and every day. 

In a clickbait driven economy - where the `truth' often depends upon the teller's agenda, and headlines are usually either hyperbolic or deceptive - for many it has become preferable to be selective consumers of information, while tuning out everything else. 

If Timothy Leary's "Turn on, tune in, drop out" was the catch-phrase of my youth then `Turn off, tune out, and drop dead!' may well be the anthem for today. 

At least, that might help explain the results of two recent surveys that examine the public's perception of the risks of avian influenza in the United States, and seasonal flu vaccine uptake among poultry workers in the UK.

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The results suggest many respondents were unaware of simple food safety practices that could reduce the risk of HPAI infection. Over half (53.7%) did not know that pasteurized milk is safer than raw milk, although almost three of four respondents (71.3%) did understand that cooking meat at high temperatures could eliminate harmful bacteria and viruses like H5N1.

Over a quarter (27%) of respondents said they were unwilling to modify their diet to reduce the risk of exposure to the virus, and more than one in four respondents (28.7%) expressed reluctance to take a potential vaccine for H5N1, even if advised by the CDC to do so.
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Rural Americans, many of whom are more likely to work or live in or near livestock industries, were less likely to accept public health measures, including vaccination and dietary changes, compared to their urban counterparts.
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In the United States, Canada, the UK, and many European countries it is recommended that those who work with poultry or swine (and cattle in the U.S.) get the seasonal flu vaccine, even though it is not designed to protect against avian or swine influenza viruses.   

Admittedly, we've seen some (slight) evidence that seasonal flu vaccination might provide some degree of protection against a severe or fatal H5Nx infection, including:

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Despite the UK government's recommendations, the following survey reveals disappointing levels of seasonal flu vaccine uptake (35%) among poultry workers in the UK. Since this survey was voluntary, there may be some bias to these numbers, so these results should be taken with a grain of salt.

DJ, crazy politicians undermine healthcare...
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Dutch Josh 2 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 4 hours 10 minutes ago at 2:20am
https://www.northernparrots.com/blog/how-have-pet-birds-been-affected-by-covid-19/ or https://www.northernparrots.com/blog/how-have-pet-birds-been-affected-by-covid-19/ ; Some owners of companion birds are concerned that Covid 19 could be passed from a human to a bird or vice versa. One lady telephoned me because she was worried that the Cockatiel that was to stay with her while its owner was on holiday could pass on the virus.

This seems to be extremely unlikely. The World Parrot Trust advises that “your bird cannot become infected by this strain of Coronavirus and so you cannot get the virus from your birds.”

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https://www.wormsandgermsblog.com/2020/11/articles/animals/birds/covid-in-animals-review-part-8-birds/ or https://www.wormsandgermsblog.com/2020/11/articles/animals/birds/covid-in-animals-review-part-8-birds/ ;This one’s easy. Birds are not susceptible to SARS-CoV-2. 

DJ, CoViD-19 is widespread in lots of (sea)mammals...https://www.wpr.org/news/fish-study-coronavirus-covid-pathogens or https://www.wpr.org/news/fish-study-coronavirus-covid-pathogens DJ, Some fish (https://pubmed.ncbi.nlm.nih.gov/32159234/ or https://pubmed.ncbi.nlm.nih.gov/32159234/ carp from Wuhan tested positive ???)

https://afludiary.blogspot.com/2025/04/the-role-of-wild-birds-in-global-highly.html or https://afludiary.blogspot.com/2025/04/the-role-of-wild-birds-in-global-highly.html ;

As recently as a decade ago, the ability of HPAI H5 viruses to be carried long distances by migratory birds was still being hotly debated, with many experts claiming birds were being falsely accused (see Bird Flu Spread: The Flyway Or The Highway?). 

While some outbreaks were clearly driven by migratory birds, until recently most birds either succumbed to the virus - or cleared the infection quickly - limiting their ability to carry the virus over long distances (see PNAS: The Enigma Of Disappearing HPAI H5 In North American Migratory Waterfowl).

By 2016, the H5N8 virus had overtaken H5N1 as the dominant subtype, and while it was more adept at hitching rides on migratory birds, it showed few signs of becoming a zoonotic threat.  H5N1 waned, as H5N8 continued to spark major epizootics in North America (2015), in Europe (2016-17), and crossed the African equator in 2017. 


DJ, CoViD weakens immunity-give more room to H5 etc.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 3 hours 55 minutes ago at 2:35am
DJ, CoViD seems NOT to be a factor in the increase of H5N1 in wild birds since 2022...

https://afludiary.blogspot.com/2025/04/the-role-of-wild-birds-in-global-highly.html or https://afludiary.blogspot.com/2025/04/the-role-of-wild-birds-in-global-highly.html (continuation from above);In 2022 we also saw a report from Defra on The Unprecedented `Order Shift' In Wild Bird H5N1 Positives In Europe & The UK, with many species of birds that were previously unaffected, suddenly dying from - or carrying - they H5N1 virus.  A year later, the virus spread into South America, and has been reported in both Antarctica and above the Arctic circle .This impressive global spread has come at a tremendous cost to both the avian population, and a large number of susceptible mammalian species (see Nature Reviews: The Threat of Avian Influenza H5N1 Looms Over Global Biodiversity).

Numbers are impossible to quantify, but hundreds of millions of wild birdshundreds of millions of captive birds, and hundreds of thousands - perhaps millions - of wild mammals have succumbed to the HPAI H5 virus over the past 5 years. 

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What was once almost exclusively an avian virus was now infecting mammalian livestock (cattle, alpacas, pigs, goats, sheep, etc.) and spilling over (and killing) dozens of species of peridomestic animals (cats, dogs, mice, foxes, skunks, along with many marine mammals). 

While surveillance and reporting is spotty at best, we are arguably witnessing the largest, most diverse, and widespread epizootic in human history.  

Even if it turns out that H5N1 doesn't have what it takes to spark a human pandemic, the damage it has done (and continues to do) to our shared ecosystem is incalculable, and the knock-on effects of these losses may not be fully appreciated for years. 

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Nearly two years ago, in Avian Flu's New Normal: When the Extraordinary Becomes Ordinary, I wrote about the numbing effect that comes with the constant barrage of HPAI H5 reports from around the world.

Events that were nearly unthinkable four years ago (e.g. Repeated trans-Atlantic introduction of avian flu from Europe, the spread of HPAI H5 across the length of South Americanumerous spillovers of H5 into mammalian species, and  > 77 human cases in the U.S. ) have somehow become routine. 

While the future course and impact of HPAI H5 remains unknown, HPAI's recent trajectory represents an escalation of its threat level, and we'd do well to take that seriously.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 3 hours 41 minutes ago at 2:49am
https://www.thailandmedical.news/news/u-s-nih-study-warns-of-lingering-damage-to-immune-and-metabolic-systems-and-increased-cancer-risk-after-covid-19-infection or https://www.thailandmedical.news/news/u-s-nih-study-warns-of-lingering-damage-to-immune-and-metabolic-systems-and-increased-cancer-risk-after-covid-19-infection 

DJ, My NON EXPERT (!!!!) view/big picture; Both CoViD-19 and H5N1 did show "the impossible" in the last 5+ years...Mpox did surprise us twice-and NOT linking it to CoViD-19 immunity damage seems to me to be "anti-science"...

A complex interaction between several diseases-transport-and several kinds of hosts is ongoing. 

One outcome is H5N1 itself has several (100+ ?) sub-clades/variants...With also an increase of other types of H5 (H5N6/H5N8...limited H5N2) spread and an increase also of H7/H9 flu-types...

Measles (so far specific for humans) is on the rise in many places and also damaging immunity. https://theconversation.com/measles-can-ravage-the-immune-system-and-brain-causing-long-term-damage-a-virologist-explains-252354 or https://theconversation.com/measles-can-ravage-the-immune-system-and-brain-causing-long-term-damage-a-virologist-explains-252354  and also CoViD is diversifying-with lots of new variants. 

Both H5N1 and CoViD may be-by now-mostly spread via (wild) animals, sometimes even without a lot/direct symptoms. 

Again-on the longer run-and because of ignoring the very major risks-both CoViD and H5-flu WILL go global into humans...with lots of other diseases also increasing. 

A major risk may be in lack of immunity defense. A "very remote health risk" (maybe even in some plants...) may find the right receptors AND a lack of immunity to become a "disease X" mega-killer. 

DJ-Climate collapse only can be stopped by nature-humans are NOT doing anything rational...Pandemics/nature do not need humans for most diseases...ignoring risks is inviting disasters...


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