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Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus |
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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DJ-I put the measles updates at the measles-2025 page
https://www.thailandmedical.news/news/breaking-novel-multidrug-resistant-bacteria-found-in-brazil-could-threaten-global-public-health or https://www.thailandmedical.news/news/breaking-novel-multidrug-resistant-bacteria-found-in-brazil-could-threaten-global-public-health link to; https://www.mdpi.com/2076-2607/13/4/897 or https://www.mdpi.com/2076-2607/13/4/897 ; AbstractThe increasing prevalence and dissemination of multidrug-resistant bacteria represent a serious concern for public health. Aeromonas caviae is a pathogenic microorganism that causes a wide spectrum of diseases in fish and humans and is often associated with aquatic environments and isolated from foods and animals. Here, we present the isolation and characterization of the V15T strain isolated from a drinking water storage tank in Rio de Janeiro, Brazil. The V15T strain has a genome length of 4,443,347 bp with an average G + C content of 61.78% and a total of 4028 open reading frames. Its genome harbors eight types of antibiotic resistance genes (ARGs) involving resistance to beta-lactamases, macrolides, and quinolones. The presence of blaMOX-6, blaOXA-427/blaOXA-504, and mutations in parC were detected. In addition, other ARGs (macA, macB, opmH, and qnrA) and multidrug efflux pumps (such as MdtL), along with several resistance determinants and 106 genes encoding virulence factors, including adherence (polar and lateral flagella), secretion (T2SS, T6SS), toxin (hlyA), and stress adaptation (katG) systems, were observed. The genome sequence reported here provides insights into antibiotic resistance, biofilm formation, evolution, and virulence in Aeromonas strains, highlighting the need for more public health attention and the further monitoring of drinking water systems. Also, the results of physiological and phylogenetic data, average nucleotide identity (ANI) calculation, and digital DNA–DNA hybridization (dDDH) analysis support the inclusion of the strain V15T in the genus Aeromonas as a new subspecies with the proposed name Aeromonas caviae subsp. aquatica subsp. nov. (V15T = P53320T). This study highlights the genomic plasticity and pathogenic potential of Aeromonas within household drinking water systems, calling for the revision of water treatment protocols to address biofilm-mediated resistance and the implementation of routine genomic surveillance to mitigate public health risks. DJ, So this bacteria is high risk and in plastic water containers...the containers that may also show up in disaster areas...The water will mix with other water-so further spreading the bacteria...
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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https://www.thailandmedical.news/news/greek-study-discovers-that-bacteria-from-the-gut-are-fueling-covid-19-severity or https://www.thailandmedical.news/news/greek-study-discovers-that-bacteria-from-the-gut-are-fueling-covid-19-severity (more links in the link). DJ-bio-chemistry ruind by virus/bacteria interactions... < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> This is what exponential spread looks like when ideology replaces immunology.
Measles is back in Alberta.
And it’s not done growing. link https://x.com/outbreakupdates/status/1911919134499078513/photo/1 or https://x.com/outbreakupdates/status/1911919134499078513/photo/1 - < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> Whooping cough cases increase in Mexico
696 confirmed cases and 37 deaths by April 2025. - | |
Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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< aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> - < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> BREAKING: Bird Flu Hits 1,009 Dairy Cattle Across 17 U.S. States; WHO Issues New Guide to Spot Human Cases and Strengthen Pandemic Preparedness. see also https://afludiary.blogspot.com/2025/04/who-guidance-surveillance-for-human.html or https://afludiary.blogspot.com/2025/04/who-guidance-surveillance-for-human.html DJ-Lots of disease normalized, masks/vaccines criminalized...Insanity the basic pandemic !
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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https://afludiary.blogspot.com/2025/04/hk-chp-reports-3-additional-h9n2-cases.html or https://afludiary.blogspot.com/2025/04/hk-chp-reports-3-additional-h9n2-cases.html ;
Although all we get is a barebones report (see chart above), the latest Hong Kong Weekly Avian Influenza Report lists 3 new H9N2 infections (1 adult, 2 children) from 3 different provinces on the Mainland. H9N2 is poorly controlled in Chinese poultry, despite the use of vaccines (see J. Virus Erad.: Ineffective Control Of LPAI H9N2 By Inactivated Poultry Vaccines - China), which has led to the creation and spread of numerous of genotypes. H9N2 also reassorts with, and often enhances, other novel influenza viruses (including H7N9, H5N1, and H5N6), making it an important co-conspirator (see Vet. Sci.: The Multifaceted Zoonotic Risk of H9N2 Avian Influenza). Seven years ago, in EID Journal: Two H9N2 Studies Of Note, we looked at two reports which suggested that H9N2 continues to evolve away from current (pre-pandemic and poultry) vaccines and is potentially on a path towards better adaptation to human hosts. While LPAI H9N2 is admittedly not at the very top of our list of pandemic concerns, the CDC has 2 different lineages (A(H9N2) G1 and A(H9N2) Y280) on their short list of influenza viruses with zoonotic potential (see CDC IRAT SCORE), and several candidate vaccines have been developed. DJ, A-symptomatic spread may be a worry; people do not take the infection serious. While it could mix/co-spread with another disease and develop into a real risk. |
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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https://www.thailandmedical.news/news/y-chromosome-may-hold-clues-to-why-covid-19-hit-some-men-and-countries-harder or https://www.thailandmedical.news/news/y-chromosome-may-hold-clues-to-why-covid-19-hit-some-men-and-countries-harder
Males are XY, females are XX...the Y-chromosome sort may be a factor in HIV, CoViD (severity). Further link; https://journals.sagepub.com/doi/full/10.1177/14034948251333236 or https://journals.sagepub.com/doi/full/10.1177/14034948251333236 --- https://www.wormsandgermsblog.com/2025/04/articles/miscellaneous/wormsgermspod/h5n1-antivirals-in-animals-should-we-use-them/ or https://www.wormsandgermsblog.com/2025/04/articles/miscellaneous/wormsgermspod/h5n1-antivirals-in-animals-should-we-use-them/ ; When does it make sense to use an antiviral to treat H5N1 flu in a dog or cat? Use of an antiviral makes sense for early treatment of known or high risk cases of H5N1 influenza where there’s a concern for development of serious disease (i.e. any infected cat, and probably infected dogs) AND when the animal can be properly treated AND when the animal can be kept isolated during and shortly after the treatment period. Basically my two main questions are: do they need it? and am I confident the animal won’t be able to infect another individual (human or animal)? If I can comfortably say yes to both of those, I think it’s reasonable to use an antiviral. Example 1: An infected cat in a household or veterinary clinic
Example 2: An infected cat that goes outside
Example 3: A potentially infected backyard chicken
DJ, We need to reduce potential hosts. NL has over 100 million farm animals (on a population of 18 million people). Less meat consumption-better price for farmers-better quality of life for (farm)animals !
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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"Do not test-do not tell"-insanity is followed by defunding public health...(to get more tax money via war-industry in the hands of a billionaire class)...not only in the US but in a lot of "neo-liberal-insanity" countries.
https://www.worldaffairsincontext.com/p/the-hidden-cost-of-tariffs-on-pharmaceuticals or https://www.worldaffairsincontext.com/p/the-hidden-cost-of-tariffs-on-pharmaceuticals ; The Hidden Cost of Tariffs on Pharmaceuticals: Prescription for a DisasterTariffs on pharmaceuticals act as hidden taxes on the sick, punishing those who are already vulnerable.Let’s examine a critical topic that affects all of us: the Trump administration’s push to impose tariffs on pharmaceutical imports. While this move may sound like just another policy headline, it could have serious consequences for millions of Americans, especially those already struggling to afford healthcare (unfortunately, there are millions of them!). DJ, US tariffs itself will increase US inflation. Most chronic disease patients allready have a low income. So they will see basic general costs go up...ON TOP OF THAT !!! A lot of medical costs-with a lot of pharma imported-may become "very high cost"...unaffordable for a lot of US citizens. And without even access to basics for the US to make those medications themselves... The US has neither the factories/staff or basic materials...Still it closed the door to import...
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Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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< aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> #H5N1
Anecdotal report:
I've heard from a reliable friend who is fluent in pandemics that a contact at CDC has said that the recent 11 (now 12) herds across 3 states (CA, NV, ID) have resulted in workers who are symptomatic.
This is not surprising. It's my belief that a great deal of Tamiflu has been handed out since the great rush of workers with symptoms occurred and then very suddenly subsided.
The news here is that the CDC contact stated that RFKjr has directed that the symptomatic workers should not be tested.
Data is clearly the first casualty of the coming pandemic. We'll be willfully flying blind. - < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> | |
Dutch Josh 2 ![]() Admin Group ![]() Joined: 21 Aug 2024 Status: Offline Points: 1837 |
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< aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw-rotate: 0; --tw-skew-x: 0; --tw-skew-y: 0; --tw-scale-x: 1; --tw-scale-y: 1; --tw-pan-x: ; --tw-pan-y: ; --tw-pinch-zoom: ; --tw-scroll-snap-strictness: proximity; --tw-gradient-from-: ; --tw-gradient-via-: ; --tw-gradient-to-: ; --tw-ordinal: ; --tw-slashed-zero: ; --tw-numeric-figure: ; --tw-numeric-spacing: ; --tw-numeric-fr: ; --tw-ring-inset: ; --tw-ring-offset-width: 0px; --tw-ring-offset-color: #fff; --tw-ring-color: hslvar--colors-blue-500 / 0.5; --tw-ring-offset-shadow: 0 0 #0000; --tw-ring-shadow: 0 0 #0000; --tw-shadow: 0 0 #0000; --tw-shadow-colored: 0 0 #0000; --tw-: ; --tw-brightness: ; --tw-contrast: ; --tw-grayscale: ; --tw-hue-rotate: ; --tw-invert: ; --tw-saturate: ; --tw-sepia: ; --tw-drop-shadow: ; --tw-backdrop-: ; --tw-backdrop-brightness: ; --tw-backdrop-contrast: ; --tw-backdrop-grayscale: ; --tw-backdrop-hue-rotate: ; --tw-backdrop-invert: ; --tw-backdrop-opacity: ; --tw-backdrop-saturate: ; --tw-backdrop-sepia: ; --tw-contain-size: ; --tw-contain-layout: ; --tw-contain-paint: ; --tw-contain-style: ; border-width: 0px; border-style: solid; border-color: black; text-align: inherit; font-size: 15px; font-family: inherit; font-feature-settings: inherit; font-variation-settings: inherit; font-weight: inherit; line-height: inherit; letter-spacing: inherit; margin: 0px; padding: 0px; appearance: ; -: none; cursor: pointer; align-items: stretch; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; min-height: 20px; min-width: 0px; : relative; : 0; overflow: ; justify-: center; outline-style: none; user-: none;"> #H5N1
So nearly 10% of recently submitted #H5N1 sequences show PB2 E627K or PB2 D701N - markers for mammalian (i.e. human) adaptation.
These samples were taken from cows, chickens, cats, and a skunk across two genotypes (B3.13 and D1.1).
PB2 D701N used to be pretty rare. PB2 E627K has been commonly found in human clusters of #H5N1.
I would expect that the percentage of samples containing these adaptive mutations will only increase with the fall/winter migration and the unmitigated spread of the virus.
Studies have indicated that if both of these mutations appear together, the dual mutations may increase virulence. https://nature.com/articles/srep14170 DJ, The fascist trumpf junta may welcome genocide by pandemic
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