A new pandemic

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   https://www.thailandmedical.news/news/another-worrisome-bird-flu-strain-h5n9-bird-flu-debuts-in-united-states or https://www.thailandmedical.news/news/another-worrisome-bird-flu-strain-h5n9-bird-flu-debuts-in-united-states 
https://afludiary.blogspot.com/2025/01/woah-california-reports-new-h5n9.html or https://afludiary.blogspot.com/2025/01/woah-california-reports-new-h5n9.html 

https://pmc.ncbi.nlm.nih.gov/articles/PMC4524050/ or https://pmc.ncbi.nlm.nih.gov/articles/PMC4524050/ ;

ABSTRACT
The novel H7N9 avian influenza virus (AIV) was demonstrated to cause severe human respiratory infections in China. Here, we examined poultry specimens from live bird markets linked to human H7N9 infection in Hangzhou, China. Metagenomic sequencing revealed mixed subtypes (H5, H7, H9, N1, N2, and N9). Subsequently, AIV subtypes H5N9, H7N9, and H9N2 were isolated. Evolutionary analysis showed that the hemagglutinin gene of the novel H5N9 virus originated from A/Muscovy duck/Vietnam/LBM227/2012 (H5N1), which belongs to clade 2.3.2.1. The neuraminidase gene of the novel H5N9 virus originated from human-infective A/Hangzhou/1/2013 (H7N9). The six internal genes were similar to those of other H5N1, H7N9, and H9N2 virus strains. The virus harbored the PQRERRRKR/GL motif characteristic of highly pathogenic AIVs at the HA cleavage site. Receptor-binding experiments demonstrated that the virus binds α-2,3 sialic acid but not α-2,6 sialic acid. Identically, pathogenicity experiments also showed that the virus caused low mortality rates in mice. This newly isolated H5N9 virus is a highly pathogenic reassortant virus originating from H5N1, H7N9, and H9N2 subtypes. Live bird markets represent a potential transmission risk to public health and the poultry industry.

DJ, US H5N9 may be a recombination of H5N1, H7N9 and H9N2. 

H7N9 is a know flu-risk in humans https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H7N9 or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H7N9 so with also H5N1 risks for more cases/spread grow...

Rick Bright reposted
Chef José Andrés 
@chefjoseandres
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Today talking to farmers, they used to pay $3.50 per chicken and now is like $15 and actually they don’t get all the chickens they request…so the price of eggs and chicken is going up big time….milk too….the bird flu is real and will get worse if we don’t take it seriously…eggs will reach 1$ per egg..
-
Dr. Angela Rasmussen
@angie_rasmussen
·
2h
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When infectious diseases are ignored or neglected—as H5N1 has been—the consequences extend far beyond public health. They can cause severe economic disruption and food insecurity/shortages.

DJ, With also climate collapse decreasing food production "we are going in the wrong direction"...

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Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 1208	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: Yesterday at 7:59am
	https://www.thailandmedical.news/news/another-worrisome-bird-flu-strain-h5n9-bird-flu-debuts-in-united-states or https://www.thailandmedical.news/news/another-worrisome-bird-flu-strain-h5n9-bird-flu-debuts-in-united-states https://afludiary.blogspot.com/2025/01/woah-california-reports-new-h5n9.html or https://afludiary.blogspot.com/2025/01/woah-california-reports-new-h5n9.html https://pmc.ncbi.nlm.nih.gov/articles/PMC4524050/ or https://pmc.ncbi.nlm.nih.gov/articles/PMC4524050/ ; ABSTRACT The novel H7N9 avian influenza virus (AIV) was demonstrated to cause severe human respiratory infections in China. Here, we examined poultry specimens from live bird markets linked to human H7N9 infection in Hangzhou, China. Metagenomic sequencing revealed mixed subtypes (H5, H7, H9, N1, N2, and N9). Subsequently, AIV subtypes H5N9, H7N9, and H9N2 were isolated. Evolutionary analysis showed that the hemagglutinin gene of the novel H5N9 virus originated from A/Muscovy duck/Vietnam/LBM227/2012 (H5N1), which belongs to clade 2.3.2.1. The neuraminidase gene of the novel H5N9 virus originated from human-infective A/Hangzhou/1/2013 (H7N9). The six internal genes were similar to those of other H5N1, H7N9, and H9N2 virus strains. The virus harbored the PQRERRRKR/GL motif characteristic of highly pathogenic AIVs at the HA cleavage site. Receptor-binding experiments demonstrated that the virus binds α-2,3 sialic acid but not α-2,6 sialic acid. Identically, pathogenicity experiments also showed that the virus caused low mortality rates in mice. This newly isolated H5N9 virus is a highly pathogenic reassortant virus originating from H5N1, H7N9, and H9N2 subtypes. Live bird markets represent a potential transmission risk to public health and the poultry industry. DJ, US H5N9 may be a recombination of H5N1, H7N9 and H9N2. H7N9 is a know flu-risk in humans https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H7N9 or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H7N9 so with also H5N1 risks for more cases/spread grow... Rick Bright reposted Chef José Andrés @chefjoseandres < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> Today talking to farmers, they used to pay $3.50 per chicken and now is like $15 and actually they don’t get all the chickens they request…so the price of eggs and chicken is going up big time….milk too….the bird flu is real and will get worse if we don’t take it seriously…eggs will reach 1$ per egg.. - Dr. Angela Rasmussen @angie_rasmussen · 2h < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> When infectious diseases are ignored or neglected—as H5N1 has been—the consequences extend far beyond public health. They can cause severe economic disruption and food insecurity/shortages. DJ, With also climate collapse decreasing food production "we are going in the wrong direction"...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 1208	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: Yesterday at 8:05am
	https://www.wormsandgermsblog.com/2025/01/articles/animals/cats/pcr-testing-for-h5n1-influenza-in-dogs-and-cats/ or https://www.wormsandgermsblog.com/2025/01/articles/animals/cats/pcr-testing-for-h5n1-influenza-in-dogs-and-cats/ ; As H5N1 avian influenza continues to spread in wild birds and spills over into domestic birds and mammals of many kinds, we’re becoming more aware of the risks to domestic mammals and there are more questions about test selection and interpretation. Fortunately, testing for H5N1 influenza is relatively straightforward. For cats and dogs, the recommended samples for testing are typically oropharyngeal swabs, plus or minus nasal swabs (plus or minus other tissue samples of the animal is deceased. What tests are currently being run by veterinary diagnostic labs? PCR is the most accessible and useful test; diagnostic labs basically offer two types of influenza PCR: matrix / pan-influenza A PCR, and strain-specific PCRs (see below). Different commercial labs offer different tests or combinations of these tests, and the tests offered may also vary by species (i.e. what’s routinely done for dogs can be different from cats). Test offerings may also change over time as labs adapt to the ever-changing situation with flu in different populations. If influenza is a consideration in your patient, check with your lab regarding which tests they will run (particularly if you are submitting samples for a respiratory PCR panel) and how to interpret the results, including whether or not the test will detect H5N1 flu if that’s a concern. - Take home message Talk to your lab to know what they can (and can’t) do in terms of testing for H5N1 flu, and follow up testing. We can’t just stop at “flu positive.” Any such result needs to be scrutinized to make sure we know the strain (or strains) involved. DJ, Worldwide more testing/sequencing would be welcomed...Both CoViD and "flu" (H5N1, H5N5, H5N6, H5N8, H5N9...) do spread in MANY species...May jump from one species to another...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 1208	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 10 hours 10 minutes ago at 10:47pm
	Outbreak Updates @outbreakupdates < aria-label="Grok s" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> President Donald Trump withdraws plans for the Environmental Protection Agency to set new limits on PFAS in drinking water supplies. The Biden administration plans aimed to set limits on six types of perfluoroalkyl and polyfluoroalkyl substances, or PFAS. - https://www.eea.europa.eu/en/about/contact-us/faqs/what-are-pfas-and-how-are-they-dangerous-for-my-health or https://www.eea.europa.eu/en/about/contact-us/faqs/what-are-pfas-and-how-are-they-dangerous-for-my-health ; They are known as ‘forever chemicals’ as they are extremely persistent in our environment and bodies. They can lead to health problems such as liver damage, thyroid disease, obesity, fertility issues and cancer. DJ, also widespread=high cost for the industry..."Just let the people die"... https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria or https://www.npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria "Living with the virus", going for "herd immunity" could have resulted in a never ending CoViD pandemic and hundreds of millions of people with serious long term health issues.. Yesterday new reports of Mpox from the Phulippines, Pakistan, UK with a worsening crisis in East DRC/Congo...Measles seems to be increasing... H5-types of flu may have mixed with "more normal" (H1N1/H3N2) human flu and very likely already spreading...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 1208	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 9 hours 41 minutes ago at 11:16pm
	https://www.thailandmedical.news/ or https://www.thailandmedical.news/ puts the global CoViD cases number at 4,300,711,275 with worldwide 38,210,660 CoViD deaths... DJ, In my eyes may be more realistic then "7 million CoViD deaths' and "post-pandemic"..."it is mild"...If "only"10% of CoViD infections result in Long CoViD we may be dealing with 430 MILLION people living with Long CoViD...More realistic may be putting that number towards 1 billion people...How often CoViD simply stays in the host is not 100% clear...very often ? Always ? Breaking the blood-brain barrier doing a lot of neurological damage ...Headaches may be "just a friendly form"... https://www.thailandmedical.news/news/influenza-positivity-rates-hit-25-percent-across-the-united-states or https://www.thailandmedical.news/news/influenza-positivity-rates-hit-25-percent-across-the-united-states and https://www.thailandmedical.news/news/h5n1-bird-flu-vaccines-are-accelerating-viral-evolution-as-currently-observed-in-china or https://www.thailandmedical.news/news/h5n1-bird-flu-vaccines-are-accelerating-viral-evolution-as-currently-observed-in-china DJ, Vaccines/anti-virals may result in evasion selection=new variants...both for CoViD and (H5N1) flu... Flu campains may be of use with limited spread, protecting limited high(er) risk groups... My non-expert question is if Non Pharma Interventions (NPI)should not be the main (low cost) strategy in pandemics ? Masks/eye protection, ventilation, avoiding crowds-goal to limit the R0/spread so a "disease will slowly go away"... Mass vaccination-and NOT going for N.P.I. "to save the economy" may prolong pandemics... HIV-AIDS pandemic so far an "old" but ongoing pandemic...CoViD a pandemic since 2020 (early spread in 2019 or maybe even earlier ? Africa ? China ?)...and we now move into a flu pandemic... With Mpox, measles, HMPV a.o. as growing problems/risks-for many species... Pandemics CAN destroy civilizations...were part of the fall of the West Roman Empire a.o. Not taking the risks serious is a high price mistake...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 1208	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 8 hours 11 minutes ago at 12:46am
	https://www.gld.nl/nieuws/8263199/griepgolf-en-kind-ziek-mag-je-als-ouder-weg-van-werk or https://www.gld.nl/nieuws/8263199/griepgolf-en-kind-ziek-mag-je-als-ouder-weg-van-werk ; Flu wave and child sick: can you leave work as a parent? -- Henri van Veen - Coughing, fever, a lame child. The flu is rampant. What if you get a call from childcare or school to pick up your child? What are your rights and obligations as parents? Employment lawyer Pascal Besselink of DAS knows what to do. Childcare and school. Influenza. A child has to go home. As a parent, can I drop everything out of my hands? Besselink: "Employment law has various regulations. For example, emergency leave; having to leave urgently because you have to pick up your child from daycare or school and there is no one else who can do that. You can also fall back on this if, for example, the neighbor calls who says you have a fire in the house or a burst water pipe. This is a short period of time, to be determined reasonably." Then you have picked up your child, let's call him Daan, and that takes a little longer than expected. Daan is not better yet. Can I get longer leave? "Then we have short-term care leave. You can take this if, for example, grandpa and grandma are not available to cover the childcare at your home. This can be done for a maximum of 2 weeks. During that period, you are entitled to 70 percent wages, capped at 70 percent of the maximum daily wage. The employer can refuse a request if there are compelling business interests and also request information from you about the necessity. For example: isn't there someone else who can take care of Daan. And then there is also long-term care leave. It is a maximum of 6 weeks, but unpaid." What most often occurs is a compromise between employer and employee. How does that work? "You indicate to your manager that something is going on at home and that you cannot be missed there. You don't know exactly how long it will take and the employer says 'I hope you'll be back tomorrow' and takes on part of the costs of your absence and you take some vacation days, for example. Something like that is then done in consultation." Does it matter whether you are the father or the mother? "No, it doesn't. A couple agrees among themselves who will pick up Daan. A man may work more hours, but if the partner is also at work at that time and he can leave, the father will pick him up. One of the two will then have to arrange this with his or her employer." Anything else? "So there are arrangements, but in practice a lot is done in consultation. It's not rocket science." DJ, Lots of European countries may have similar rules..US/UK situation "not that good"... Pandemic-prevention NEEDS good social rules...You want to avoid disease spread on the job...To sack sick workers may result in not getting "the best" workers... Good gouvernance=good laws !

A new pandemic

ABSTRACT

Flu wave and child sick: can you leave work as a parent?

Childcare and school. Influenza. A child has to go home. As a parent, can I drop everything out of my hands?

Then you have picked up your child, let's call him Daan, and that takes a little longer than expected. Daan is not better yet. Can I get longer leave?

What most often occurs is a compromise between employer and employee. How does that work?

Does it matter whether you are the father or the mother?

Anything else?