Latest News - Oropouche virus disease

Oropouche virus disease

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Topic: Oropouche virus disease

Posted By: Dutch Josh 2
Subject: Oropouche virus disease
Date Posted: 10 Sep 2024 at 10:28pm

https://x.com/CoronaHeadsUp -

https://x.com/CoronaHeadsUp/status/1833388203702735153 -

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Americas: Oropouche virus cases near 10,000 "So far, Brazil has reported 11 fetal deaths, 3 spontaneous miscarriages, and 4 cases involving congenital anomalies."

link; https://www.cidrap.umn.edu/oropouche-virus/oropouche-cases-americas-near-10000 - https://www.cidrap.umn.edu/oropouche-virus/oropouche-cases-americas-near-10000 or https://www.cidrap.umn.edu/oropouche-virus/oropouche-cases-americas-near-10000 ;Since its last update at the start of August, the Pan American Health Organization (PAHO) in https://www.paho.org/en/documents/epidemiological-update-oropouche-americas-region-6-september-2024 - said six countries in the Americas region have reported 1,774 more Oropouche virus cases, mostly from Brazil, Peru, and Cuba.

In a new development, the Dominican Republic reported 33 cases from retrospective testing, making it the second-most affected country in the Caribbean subregion. In August, Canada and the United States each reported imported infections.

Spread mainly by certain biting midges, the surge in Oropouche virus activity has raised concerns due to outbreaks well beyond the usual affected areas and reports of severe fetal outcomes, including deaths and congenital malformations.

So far, Brazil has reported 11 fetal deaths, 3 spontaneous miscarriages, and 4 cases involving congenital anomalies, PAHO said.

See also https://en.wikipedia.org/wiki/Oropouche_orthobunyavirus - https://en.wikipedia.org/wiki/Oropouche_orthobunyavirus or https://en.wikipedia.org/wiki/Oropouche_orthobunyavirus

DJ-As a non-expert;

-Oropouche virus detected in a larger area

-Bringing more severe disease

Another aspect is insect spread-like Blue Tongue Virus Disease and possibly Mpox...(among a lot of diseases-Malaria most well known and deathly).

Climate collapse may bring "Amazon-like conditions" to a wider area-so the area where the virus can be active gets larger. Also storms may transport infected insects to areas that do not normally see these kinds of virus.

Replies:

Posted By: Dutch Josh 2
Date Posted: 28 Oct 2024 at 11:29am

https://www.thailandmedical.news/news/study-validates-that-it-s-a-new-strain-of-oropouche-virus-that-is-wreaking-havoc-across-brazil-and-soon-globally - https://www.thailandmedical.news/news/study-validates-that-it-s-a-new-strain-of-oropouche-virus-that-is-wreaking-havoc-across-brazil-and-soon-globally or https://www.thailandmedical.news/news/study-validates-that-it-s-a-new-strain-of-oropouche-virus-that-is-wreaking-havoc-across-brazil-and-soon-globally

link to https://www.nature.com/articles/s41591-024-03300-3 - https://www.nature.com/articles/s41591-024-03300-3 or https://www.nature.com/articles/s41591-024-03300-3 ;

Abstract

The Brazilian western Amazon is experiencing its largest laboratory-confirmed Oropouche virus (OROV) outbreak, with more than 6,300 reported cases between 2022 and 2024.

In this study, we sequenced and analyzed 382 OROV genomes from human samples collected in Amazonas, Acre, Rondônia and Roraima states, between August 2022 and February 2024, to uncover the origin and genetic evolution of OROV in the current outbreak.

Genomic analyses revealed that the upsurge of OROV cases in the Brazilian Amazon coincides with spread of a novel reassortant lineage containing the M segment of viruses detected in the eastern Amazon region (2009–2018) and the L and S segments of viruses detected in Peru, Colombia and Ecuador (2008–2021).

The novel reassortant likely emerged in the Amazonas state between 2010 and 2014 and spread through long-range dispersion events during the second half of the 2010s. Phylodynamics reconstructions showed that the current OROV spread was driven mainly by short-range (< 2 km) movements consistent with the flight range of vectors.

Nevertheless, a substantial proportion (22%) of long-range (>10 km) OROV migrations were also detected, consistent with viral dispersion by humans.

Our data provide a view of the unprecedented spread and evolution of OROV in the Brazilian western Amazon region.

DJ, see also https://en.wikipedia.org/wiki/Oropouche_fever#Epidemiology - https://en.wikipedia.org/wiki/Oropouche_fever#Epidemiology or https://en.wikipedia.org/wiki/Oropouche_fever#Epidemiology ;

Between December 2023–June 2024, large Oropouche virus disease outbreaks were recognized in areas with known endemic disease, and the virus emerged in new areas in South America and Cuba where it had not been historically reported.^{https://en.wikipedia.org/wiki/Oropouche_fever#cite_note-17 - https://en.wikipedia.org/wiki/Oropouche_fever#cite_note-cdchan515-14 - ORO fever occurs mainly during the rainy seasons, because there is an increase in https://en.wikipedia.org/wiki/Breeding_in_the_wild - breeding sites in the vector populations.^{https://en.wikipedia.org/wiki/Oropouche_fever#cite_note-:0-9 - https://en.wikipedia.org/wiki/Oropouche_fever#cite_note-:0-9 -}}