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| Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus |
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| Topic - New (type of) CoViD vaccine Posted: 22 Aug 2024 at 11:09pm By Dutch Josh 2 |
 < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> A step towards a nasal universal flu vaccine link; https://x.com/EricTopol/status/1826648221395157126/photo/1 or https://x.com/EricTopol/status/1826648221395157126/photo/1 (DJ- does not work-for me-no link) < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> The study focuses on developing a next-generation influenza vaccine that can provide broader protection against both seasonal and pre-pandemic influenza viruses. Current influenza vaccines need to be updated annually due to changes in the viruses, and they do not offer protection against strains with pandemic potential.
The octavalent COBRA-based vaccine, administered intranasally with the c-di-AMP adjuvant, was able to induce broad and protective immune responses in both pre-immune and naive ferrets. The pre-existing immunity in some ferrets further enhanced the vaccine's effectiveness, likely due to the boosting of cross-reactive antibodies, especially those targeting the more conserved HA stem region. another link https://www.openread.academy/en/paper/reading?corpusId=507012294 or https://www.openread.academy/en/paper/reading?corpusId=507012294 ... DJ-This is about a nasal flu-vaccine...however it may offer perspective also on a "nose spray" offering protection against CoViD... DJ-A very important factor on vaccines are costs...If the price (profits) are high only a limited number of people can afford it...When you want to END a pandemic vaccines need to be available for ALL !!! (And tax-paid-NO profits/shareholders getting rich !) Another aspect may have to be to get pandemic diseases in non-human hosts under control...In part less meat consumption will help-less farm animals=less spread... But we have to learn more on disease spread in wild(er) animals...If H5N1 is in ducks in the park near you-without getting the ducks ill it still can get into the cat eating a death duck, a dog eating duck droppings... |
