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| Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus |
Post Reply - H5N1/flu (other types) |
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| Topic - H5N1/flu (other types) Posted: 11 Jul 2024 at 11:58pm By Dutch Josh |
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< aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> Called it. CDC is now recommending that all wastewater surveillance groups develop and implement protocols to specifically test for H5N1. -  < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> "These results indicate that PB2 Q591R or D701N, but not the other substitutions tested here, act in a similar manner to E627K and specifically enable the viral polymerase to utilize human ANP32A or -B proteins as a cofactor." link; https://journals.asm.org/doi/10.1128/jvi.00213-23 or https://journals.asm.org/doi/10.1128/jvi.00213-23  < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> "First, an update on #H5N1 avian influenza.
Last week, the United States reported a fourth human case of H5N1 following exposure to infected dairy cows.
Cambodia also reported two cases in children who had contact with sick or dead chickens.
For the moment, no human-to-human transmission has been reported, which is why WHO continues to assess the risk to the general public as low.
However, our ability to assess and manage that risk is compromised by limited surveillance for influenza viruses in animals globally.
Understanding how these viruses are spreading and changing in animals is essential for identifying any changes that might increase the risk of outbreaks in humans, or the potential for a pandemic"- DJ, The WHO is "not a front running organization" it needs funding by governments... Very likely there is a lot of mammal-to-mammal spread already in lots of places...(mice, rats...cows ???) So in my NON EXPERT view it is just a matter of time before we see H5N1 going H2H = Human to Human... Increase of CoViD -decreasing immunity- does not help. The CoViD pandemic is NOT !!!! over ! It is even getting worse... It is impossible to get even a basic idea of how widespread H5N1 is in "wild animals"...but lots of species can catch H5N1, most of them can spread it...and some species may not develop symptoms... How bad H5N1 will be in humans is unclear...it may develop as a "bad flu"...However co-infections may result in worse outcomes. "Flu-Rona" -H5N1 and CoViD - on a large scale will be to much for most public health care...
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