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| Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus |
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| Topic - H5N1/flu (other types) Posted: 30 Oct 2024 at 2:36pm By Dutch Josh 2 |
 < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> This is an unsurprising, but worrisome development. Pigs have long been thought of as a stepping stone in evolutionary process that influenza viruses take to adapt from infecting birds to humans. link [url]https://www.statnews.com/2024/10/30/h5n1-bird-flu-found-in-oregon-pig-reassortment-threat-human-transmission/?utm_medium=email&_hsenc=p2ANqtz--i5PwjVKadHyLQ6ERnXxsbj9ia7KovS7iM-o_79U-oWqX8EUAVVmlHmP1NFcx7prdSVrkSDYN7nFVzfZ4z_itXiGZP_g&_hsmi=331600440&utm_content=331600440&utm_source=hs_email[url] or https://www.statnews.com/2024/10/30/h5n1-bird-flu-found-in-oregon-pig-reassortment-threat-human-transmission/?utm_medium=email&_hsenc=p2ANqtz--i5PwjVKadHyLQ6ERnXxsbj9ia7KovS7iM-o_79U-oWqX8EUAVVmlHmP1NFcx7prdSVrkSDYN7nFVzfZ4z_itXiGZP_g&_hsmi=331600440&utm_content=331600440&utm_source=hs_email H5N1 bird flu virus has been found in a pig on a farm in Oregon, the first time the virus has been seen in a pig in the United States, the U.S. Department of Agriculture reported Wednesday. The pig, one of five on the farm, which is experiencing an H5N1 outbreak in poultry, did not display signs of illness. Two others tested negative and testing is ongoing on the other two. All five were euthanized to allow for study of whether the animals were truly infected. Pigs are sometimes called a “mixing vessel” for flu viruses, because they can be infected with both bird flu viruses and human flu viruses. If the animals are co-infected at the same time with two or more viruses, the viruses can swap genes, potentially creating a hybrid virus that is better able to spread to and among people than bird flu viruses typically are. This phenomenon, called reassortment, is what gave rise to the 2009 H1N1 pandemic. DJ, Not unexpected-H5N1 may be in lots of mammals...but increasing further risks...  < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> H5N1 on a mixed farm, with - from the description- direct contact between poultry and pigs. Not a desirable situation. Would be good to know how many of such farms there are. Entry of H5N1 into the pig population would crank up level of concern https://aphis.usda.gov/news/agency-announcements/federal-state-veterinary-agencies-share-update-hpai-detections-oregon - https://afludiary.blogspot.com/2024/10/usda-aphis-reports-1st-detection-of.html or https://afludiary.blogspot.com/2024/10/usda-aphis-reports-1st-detection-of.html ; With the caveat that this is appears to be a limited outbreak, we have the first official word of HPAI H5N1 spillover from poultry to swine on an American farm.
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While that may be good news for the pig, it doesn't prevent the virus from reassorting with other (swine or human) influenza viruses, or potentially transmitting to other hosts. DJ, More testing would detect more cases...asymptomatic spread in some wild birds, pigs is "bad news"-harder to detect...
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