Corona/CoViD-news

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Cat in the Hat   
@_CatintheHat
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7h
< aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;">
This is a neat couple of charts from Bob Hawkins where he compares Covid test positivity rates to estimated Covid prevalence across last winter.

Right now, test positivity is 6.1%…

…so Covid prevalence could be ~2.3%.

That’s 1 in 43 people infected.

link;https://bhawkins3.substack.com/p/covid-situation-report-nov-7-2024 or https://bhawkins3.substack.com/p/covid-situation-report-nov-7-2024 ;
This week brings good news with the data showing Covid levels falling across England, Scotland and Wales.
In England, the Covid test positivity rate, hospital admissions and case rates all fell this week, and are at relatively low levels. All regions saw hospital admission rates fall.
In Scotland, Covid levels decreased across all measures, including admissions to hospital, relative to the most recent peak in July. 
Over the past week, hospital admissions in Wales have decreased, yet they continue to be moderately high.
Regrettably, the Northern Ireland Surveillance Report for this week has not yet been released, hence no update can be provided.

DJ, https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?time=2023-11-05..latest&country=USA~GBR~NLD or https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?time=2023-11-05..latest&country=USA~GBR~NLD excess deaths still high-with the UK however september 1 excess deaths -1%-so below the long term average !

Still for CoViD statistics on testing/sequencing only show severe, older (in time) cases from hospital...We may also miss "Flu-Rona" cases untill those co-infections show up in hospital/increase of deaths...

DJ-the MSM fake-news-machine is NOT interested in information, only profits...With that a main tool to get a grip on pandemics; information/communication is gone...

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Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 902	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 08 Nov 2024 at 10:43pm
	Cat in the Hat @_CatintheHat · 7h < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> This is a neat couple of charts from Bob Hawkins where he compares Covid test positivity rates to estimated Covid prevalence across last winter. Right now, test positivity is 6.1%… …so Covid prevalence could be ~2.3%. That’s 1 in 43 people infected. link;https://bhawkins3.substack.com/p/covid-situation-report-nov-7-2024 or https://bhawkins3.substack.com/p/covid-situation-report-nov-7-2024 ; This week brings good news with the data showing Covid levels falling across England, Scotland and Wales. In England, the Covid test positivity rate, hospital admissions and case rates all fell this week, and are at relatively low levels. All regions saw hospital admission rates fall. In Scotland, Covid levels decreased across all measures, including admissions to hospital, relative to the most recent peak in July. Over the past week, hospital admissions in Wales have decreased, yet they continue to be moderately high. Regrettably, the Northern Ireland Surveillance Report for this week has not yet been released, hence no update can be provided. DJ, https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?time=2023-11-05..latest&country=USA~GBR~NLD or https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?time=2023-11-05..latest&country=USA~GBR~NLD excess deaths still high-with the UK however september 1 excess deaths -1%-so below the long term average ! Still for CoViD statistics on testing/sequencing only show severe, older (in time) cases from hospital...We may also miss "Flu-Rona" cases untill those co-infections show up in hospital/increase of deaths... DJ-the MSM fake-news-machine is NOT interested in information, only profits...With that a main tool to get a grip on pandemics; information/communication is gone...

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 902	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 10 Nov 2024 at 10:18pm
	tern @1goodtern · 10h < aria-expanded="false" aria-haspopup="menu" aria-label="More" role="" ="-175oi2r r-1777fci r-bt1l66 r-bztko3 r-lrvibr r-1loqt21 r-1ny4l3l" -testid="caret" ="" style="text-align: inherit; font-size: inherit; font-family: inherit; align-items: stretch; border-width: 0px; border-style: solid; border-color: black; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 0; list-style: none; margin: 0px; min-height: 20px; min-width: 0px; padding: 0px; : relative; : 0; overflow: ; justify-: center; cursor: pointer; outline-style: none; user-: none;"> Well it's another study that comes like a kick in the gut. Covid infection in pregnant mothers disrupts immune balance, alters fetal brain cells and increases offspring's risk of neurodevelopmental disorders. link; https://www.nature.com/articles/s41380-024-02822-z or https://www.nature.com/articles/s41380-024-02822-z ; Maternal COVID-19 infection increases the incidence of neurodevelopmental disorders (NDDs) in offspring, although the underlying mechanisms have not been elucidated. This study demonstrated that COVID-19 infection during pregnancy disrupted the balance of maternal and fetal immune environments, driving alterations in astrocytes, endothelial cells, and excitatory neurons. A risk score was established using 47 unique genes in the single-cell transcriptome of gestational mothers. The high risk score in CD4 proliferating T cell level served as an indicator for increased risk of offspring NDDs. Summary-based Mendelian randomization and phenome-wide association study analyses were conducted to identify the causal association of the transcriptional changes with the increased risk of offspring NDDs. Additionally, 10 drugs were identified as potential therapeutic candidates. Our findings support a model where the maternal COVID-19 infection changed the levels of CD4 proliferating T cells, leading to the alterations of astrocytes, endothelial cells, and excitatory neurons in offspring, contributing to the increased risk of NDDs in these individuals. DJ-T-cell damage... Jane Johnson 〓〓 @JaneJohnsonBakr · 10h Replying to @1goodtern Or indeed leads to stillbirth, as happened to my poor niece. DJ, "living with the virus" is getting killed by the virus...on the long run. https://www.thailandmedical.news/news/how-autoimmune-responses-in-the-brain-could-explain-long-covid-symptoms or https://www.thailandmedical.news/news/how-autoimmune-responses-in-the-brain-could-explain-long-covid-symptoms with a link to; https://www.sciencedirect.com/science/article/pii/S2090123224005307 or https://www.sciencedirect.com/science/article/pii/S2090123224005307 ; Conclusions The current study provides the first evidence indicating that autoimmune responses directed at neuronal proteins play a key role in Long COVID disease. Brain reactive autoantibodies directed at MBP, MOG, tubulin, CP2, and synapsin are elevated in patients with Long COVID disease indicating a neuro-autoimmune pathophysiology of this condition. The severity of the physio-affective phenome (CFS, depressive and anxiety dimensions), which represents a major dimension of Long COVID, is significantly predicted by increased IgM/IgA-synapsin, IgA/IgG-MBP, IgG-MOG, and CRP and AOPP levels. The current study is a proof of concept and mechanism study that autoimmune, inflammatory, and oxidative responses play a significant role in the pathophysiology of Long COVID disease, and in the CFS and affective symptoms (the physio-affective phenome) due to Long COVID. Our findings highlight the pivotal role of immune-inflammatory responses in LC and align with evidence-based psychiatry's focus on integrating biological markers for guiding diagnosis and treatment [78]. By addressing the fundamental pathways that connect immunological dysregulation to psychiatric disorders, such integration enhances clinical practice. DJ, Disease often is the result of immunity system fighting an infection....Sometimes the virus/bacteria NEEDS a strong immune reaction. However over-reaction/ immunity going on after the disease is gone or damage by the immune reaction itself can be a problem.

Dutch Josh 2 Members Profile Send Private Message Find Members Posts Add to Buddy List Admin Group Joined: 21 Aug 2024 Status: Offline Points: 902	Post Options Post Reply Quote Dutch Josh 2 Report Post Thanks(0) Quote Reply Posted: 16 Nov 2024 at 5:50am
	https://www.thailandmedical.news/news/scientists-warn-a-new-sars-cov-2-lineage-that-will-have-more-mutations-and-pose-challenges-will-likely-emerge-early-2025 or https://www.thailandmedical.news/news/scientists-warn-a-new-sars-cov-2-lineage-that-will-have-more-mutations-and-pose-challenges-will-likely-emerge-early-2025 with link to; https://www.preprints.org/manuscript/202411.0947/v1 or https://www.preprints.org/manuscript/202411.0947/v1 and https://www.thailandmedical.news/news/china-identifies-new-feline-coronavirus-that-is-extremely-lethal-and-could-pose-a-threat-to-humans or https://www.thailandmedical.news/news/china-identifies-new-feline-coronavirus-that-is-extremely-lethal-and-could-pose-a-threat-to-humans link tohttps://onlinelibrary.wiley.com/doi/10.1155/2024/4162458 or https://onlinelibrary.wiley.com/doi/10.1155/2024/4162458 DJ-my non-expert view; biggest risks -non human spread of CoViD goes on... -lack of testing/sequencing=missing developments Resulting in CoViD come-back with variants for wich we have no protection...mixing with lots of other diseases...The "new pandemic" is loss of immunity...may be one of the reasons why the US is now seeing that much human H5N1 cases...

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