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Marburg outbreak Rwanda/Central Africa

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Dutch Josh 2 View Drop Down
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    Posted: 29 Sep 2024 at 2:12am
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🚨 Update on 1st #Marburg outbreak in #Rwanda: - 26 cases, 6 deaths—likely undetected for a while. - First-ever reported cases in Rwanda. - Cases centered in/around #Kigali (pop. 1.2M), raising spread concerns due to intl. flights. - Reported Health worker deaths highlight urgent need for better protection. - No approved treatments or vaccines yet, but mAbs & vaccines in development. Swift action needed for stronger surveillance, testing, community engagement, implementation of prevention and control measures and optimizing supportive care.

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Many questions about the #Marburg outbreak in #Rwanda - when was the first suspect case - how many contacts of cases are being followed - how many people have been tested - given proximity of Rwanda to countries which have historically had outbreaks, important to know if any cases have had recent travel - what kind of supportive care are patients receiving

See also https://flutrackers.com/forum/forum/africa/africa-all-other-diseases/997602-rwanda-moh-announces-a-few-marburg-cases-september-27-2024-who-confirms-26-cases-6-deaths?view=stream  or https://flutrackers.com/forum/forum/africa/africa-all-other-diseases/997602-rwanda-moh-announces-a-few-marburg-cases-september-27-2024-who-confirms-26-cases-6-deaths?view=stream 

DJ, https://en.wikipedia.org/wiki/Marburg_virus_disease#Epidemiology or https://en.wikipedia.org/wiki/Marburg_virus_disease#Epidemiology NOT new to Africa...but spreading in an urban enviroment (Kigali) makes it a high risk outbreak....

Mpox and lots of other diseases also in the region...

Very serious ! Another Public Health Emergency of International Concern (WHO ???) in the making ? 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 04 Oct 2024 at 12:13am
https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/997939-cidrap-rwanda-confirms-more-marburg-cases-plans-vaccine-trial?view=stream  or https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/997939-cidrap-rwanda-confirms-more-marburg-cases-plans-vaccine-trial?view=stream ; (latest) ;

Rwanda confirms more Marburg cases, plans vaccine trial


Lisa Schnirring


Today at 3:55 p.m.

Marburg

Viral Hemorrhagic Fever As Rwanda battles its first Marburg virus outbreak, the country’s health ministry yesterday reported seven more cases, along with one more death. At briefings today, the country’s health minister shared more details about the outbreak, including that a vaccine trial is slated to begin soon.

In other developments, German officials reported negative results on two travelers who returned from Rwanda and were isolated in Hamburg due to a history of exposure in a Rwandan hospital where Marburg patients were being treated.

29 health workers among confirmed cases


The new illness confirmations and deaths bring Rwanda’s Marburg virus total to 36 cases, 11 of them fatal, making it one of the world’s biggest outbreaks involving the virus.

At an Africa Centres for Disease Control and Prevention (Africa CDC) media briefing today, Rwanda’s health minister, Sabin Nsanzimana, MD, PhD, said 29 (80%) of the patients are healthcare workers. Currently, 25 people are being treated in isolation. Health officials have identified 323 contacts for monitoring.

Like past Marburg outbreaks in other countries, Rwanda’s came to the attention of health officials when healthcare workers got sick. The virus is known to transmit through contact with infected body fluids. He noted that the first two patients didn’t respond to usual treatment for other conditions such as malaria, which has a similar initial clinical presentation.

Many of the patients are part of a cluster of people who had close contact in the intensive care unit (ICU) of a hospital where the probable index patient was treated.

At a World Health Organization (WHO) briefing today, Brian Chirombo, MD, MPH, said the index patient died on September 8 and that the outbreak involves patients at two Kigale hospitals, King Faisal and University Teaching Hospital.

Nsanzimana said the ministry expects to receive about 5,000 doses of remdesivir to provide advanced treatment for Marburg patients.

He also said officials expect to launch a vaccine trial in the days ahead, and details about the vaccine and the official launch date will be announced soon. Currently, there are no approved specific Marburg virus treatments or vaccines.

The epidemiologic investigation and genetic sequencing are still under way. He characterized the outbreak as “controlled but not contained.”

Negative tests for German passengers, CDC alert for health providers


Yesterday, German health officials transported two train passengers to a hospital in Hamburg for testing after a history of exposure in a Rwandan medical facility where Marburg patients are being treated.

The European Centre for Disease Prevention and Control (ECDC) said today that it has been in close contact with German public health authorities, who reported today that the tests were negative.

It said the risk of Marburg illness in European residents traveling or living in affected parts of Rwanda is still considered low, but the risk of exposure in healthcare settings there is moderate. It urged travelers to avoid contact with symptomatic people and the dead bodies of infected people.

Meanwhile, the US Centers for Disease Control and Prevention (CDC) today issued a Health Alert Network notice to health providers, filling them in about the outbreak and urging them to be alert to the possibility of imported cases.

Though most of Rwanda’s cases involve health workers, the CDC noted that there are also cases that aren’t linked to known transmission chains, suggesting that additional cases may have been undetected or unreported.

Though cases have been reported from seven of Rwanda’s districts, three in Kigali have reported the highest number of cases.
​
DJ, One of the few options left to fight pandemics is trying to spread info;
https://en.wikipedia.org/wiki/Rwanda_Marburg_virus_disease_outbreak or https://en.wikipedia.org/wiki/Rwanda_Marburg_virus_disease_outbreak 

Will Marburg-Virus-Disease (MVD) spread outside Rwanda ? YES-it will spread into the Central African Region...(DJ-my view)...it may be impossible to contain it...

Lots of other diseases/disasters/wars in the region...Almost NO !!! healthcare...
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Will Marburg spread outside Africa ? 

DJ-If it manages to reach countries that also see tourism/travel (Kenya, South Africa) 
it can spread further...

Like with other diseases "economy first" means NO testing before people get on a plane...

Stupid is the new normal-we are doing all we can to create more pandemics...At the same time investing trillions in endless wars, getting 0,1% of people even more rich...

News is under control/censorship...pandemics are out of control...just like wars, climate collapse...

CoViD gives other diseases extra room to spread by damaging (destroying HIV-like ???) immunity...
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh 2 Quote  Post ReplyReply Direct Link To This Post Posted: 12 Oct 2024 at 11:11pm
https://www.thailandmedical.news/news/latest-rwanda-updates-shows-that-marburg-virus-has-killed-14-and-infected-61-individuals or https://www.thailandmedical.news/news/latest-rwanda-updates-shows-that-marburg-virus-has-killed-14-and-infected-61-individuals 
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https://en.wikipedia.org/wiki/Rwanda_Marburg_virus_disease_outbreak or https://en.wikipedia.org/wiki/Rwanda_Marburg_virus_disease_outbreak ;

As of October 3, cases had been reported in seven of the 30 districts in Rwanda. Three districts in Kigali Province reported the highest number of cases, namely Gasabo DistrictKicukiro District and Nyarugenge District. Other districts included Nyagatare District and Gatsibo District in the Northeast, which border Tanzania, site of the 2023 Tanzania Marburg virus disease outbreak as well as Rubavu District in the Northwest bordering Democratic Republic of the Congo and Kamonyi District, which is adjacent to Kigali in the center.[18]

DJ...so far outbreak seems to-now- be local-in Kigali-Rwanda...maybe new cases even linked to hospital spread...

Kigali has a population of 1,8 million+, Rwanda is involved in wars in the DRC/Congo border...Health Care is "limited"....

DJ-If there are serious problems there is a risk that help would move away/out...Simply not able to do much - to much risks involved... 

Wars and ebola-like diseases are a bad mix. There are vaccines for Ebola...NOT for the Marburg viral disease...

It comes on top of HIV/AIDS, Mpox, ignored CoViD problems...
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