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Mpox Discussion Forum: Latest News & Information Regarding the Clade 1b Mpox Virus

On M-pox

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Dutch Josh View Drop Down
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    Posted: 03 Jul 2024 at 7:23am
https://en.wikipedia.org/wiki/Mpox# or https://en.wikipedia.org/wiki/Mpox# ;
Mpox (formerly known as monkeypox)[6] is an infectious viral disease that can occur in humans and other animals.[1] Symptoms include a rash that forms blisters and then crusts over, fever, and swollen lymph nodes.[1] The illness is usually mild and most of those infected will recover within a few weeks without treatment.[5] The time from exposure to onset of symptoms ranges from five to twenty-one days and symptoms typically last from two to four weeks.[2] Cases may be severe, especially in children, pregnant women or people with suppressed immune systems.
A further link https://www.who.int/news-room/fact-sheets/detail/monkeypox or https://www.who.int/news-room/fact-sheets/detail/monkeypox ;

  • Mpox can be transmitted to humans through physical contact with someone who is infectious, with contaminated materials, or with infected animals.
  • Identifying mpox can be difficult as other infections and conditions can look similar. It is important to distinguish mpox from chickenpox, measles, bacterial skin infections, scabies, herpes, syphilis, other sexually transmissible infections, and medication-associated allergies. Someone with mpox may also have another sexually transmissible infection such as herpes. Alternatively, a child with suspected mpox may also have chickenpox. For these reasons, testing is key for people to get treatment as early as possible and prevent further spread.
  • Getting an mpox vaccine can help prevent infection. The vaccine should be given within 4 days of contact with someone who has mpox (or within up to 14 days if there are no symptoms). 

    It is recommended for people at high risk to get vaccinated to prevent infection with mpox, especially during an outbreak. This includes:

    • health workers at risk of exposure
    • men who have sex with men
    • people with multiple sex partners
    • sex workers.

    Persons who have mpox should be cared for away from other people.

  • Mpox is a zoonosis, a disease that is transmitted from animals to humans, with cases often found close to tropical rainforests where there are animals that carry the virus. Evidence of monkeypox virus infection has been found in animals including squirrels, Gambian pouched rats, dormice, different species of monkeys and others. 

DJ...would an earlier CoViD infection -in some sort of animals- increase risk for catching M-pox ? 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Pixie Quote  Post ReplyReply Direct Link To This Post Posted: 03 Jul 2024 at 7:27am
The story reeks of ewww,but shows how easy transmission double,triple quickly

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 03 Jul 2024 at 7:37am
https://www.cdc.gov/poxvirus/mpox/veterinarian/mpox-in-animals.html or https://www.cdc.gov/poxvirus/mpox/veterinarian/mpox-in-animals.html ;

In 2003, an outbreak of mpox in domesticated prairie dogs occurred after they shared bedding and caging with a shipment of infected small mammals from West Africa. This led to 47 human cases in six states in the United States. This was the first time that human mpox was reported outside of Africa. Separating animals and people who are infected or have been exposed to mpox can help stop mpox from spreading further.

What We Know About Mpox in Animals

  • Monkeypox virus can infect a wide range of mammal species, including monkeys, anteaters, hedgehogs, prairie dogs, squirrels, and shrews.
  • We are still learning which species of animals can get infected with Monkeypox virus. While we do not know if reptiles, amphibians, or birds can get mpox, it is unlikely since these animals have not been found to be infected with other orthopoxviruses.
  • Not all animals have a rash when they have mpox.
  • Infected animals can spread Monkeypox virus to people and other animals, and it is possible that people who are infected can spread Monkeypox virus to animals through close contact.
  • Monkeypox virus can be found in the rash caused by mpox (scabs, crusts, fluids) and infected body fluids, including respiratory secretions, and potentially in urine (pee) and feces (poop).

What We Know About Mpox in Pets

  • We don’t know for sure if pets like dogs and cats can be infected with Monkeypox virus, but it may be possible.
  • People with mpox could possibly spread the virus to pets through close contact, including petting, cuddling, hugging, kissing, licking, sharing sleeping areas, and sharing food.

No pets or other animals were confirmed to have mpox during the global mpox outbreak that began in 2022.

How to Care for Pets if You Have Mpox

  • If you have mpox, avoid contact with animals, including pets, domestic animals, and wildlife to prevent spreading the virus.
    • Ask friends or family members who live in a separate home to care for your animals until you fully recover. After you recover, clean and disinfect your home before bringing healthy animals back.
  • People who are at increased risk for severe mpox should not care for animals that had close contact with a person with mpox. This includes
    • People with weakened immune systems
    • Pregnant people
    • Young children
    • People with a history of atopic dermatitis or eczema

Steps to Take if You Think Your Pet Has Mpox

  • Possible symptoms of mpox in pets include rash, lethargy, lack of appetite, coughing, bloating, nasal and/or eye secretions or crust, fever, and/or pox-like skin sores (may initially resemble a pimple or blister first).
  • If your pet had close contact with a person with probable or confirmed mpox and they have a new rash or two other symptoms, get your pet tested for mpox.
  • Call your veterinarian if you notice an animal appears sick within 21 days after contact with a person with probable or confirmed mpox. A veterinarian can help notify your state public health veterinarian [136 KB, 7 pages] or state animal health official, who can assist with getting high-risk pets tested.
  • Separate the sick animal from other pets and animals.
  • Limit direct contact between the animal and people for at least 21 days until they are fully recovered or a veterinarian tells you it’s safe.
  • Wash your hands often and wear clothing that covers your skin when caring for and cleaning up after sick animals. Wash your clothes after caring for sick animals.
  • Disinfect animal bedding, enclosures, food dishes, and any other items in direct contact with infected animals.
  • Do not shake soiled laundry and bedding (including disposable rodent bedding).

For information on how to clean and disinfect your home when someone is sick, visit Cleaning and Disinfecting.


DJ, The info I am looking for is spread of M-pox in animals...ways of spreading, symptoms...

Should we test more in (what type of) animal(s) ? 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 03 Jul 2024 at 7:47am
....One runs risks if one jumps from one bedpartner to another...Not only for Mpox but lots of (Sexually Transmitted) Diseases...

Good info is supposed to stop the high risk behavior...somehow it not always sticks...

M-pox may spread via contact, infected fluids on doorknobs, watertaps...Some indications out of DRC to possible aerosol spread ??? (The number of schoolchildren infected is high in certain regions). 

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00059-9/fulltext or https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00059-9/fulltext ;
The mode of transmission for human monkeypox virus (MPXV) has thus far been considered to be direct physical contact with lesions or the fluids contained within them during intimate contact. However, ongoing outbreaks since 2022 have triggered new debates regarding roles of other possible transmission modes of MPXV, such as the airborne route.
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Bruno Hernaez and colleagues reported that in their study of 44 patients with symptomatic mpox at two health centres in Spain, high loads of MPXV DNA were identified in 35 (85%) of 41 saliva samples and that infectious MPXV was recovered from 22 (67%) of 33 saliva samples positive for MPXV DNA. The reported maximum viral load in saliva samples of patients reached approximately 1×10 copies of viral genome per mL, and the minimum size of respiratory particles carrying the virus in those viral load conditions was calculated to be more than 25 μm, by use of aerosol dynamics theories and the reported viral load (appendix).   
Hugh Adler and colleagues reported on the viral loads (denoted by Ct values) of MPXV identified in the upper respiratory tracts of seven patients in the UK. The viral loads of the patients, based on these Ct values, were estimated to be less than 106 copies per mL.  The minimum size of respiratory particles carrying MPXV virions was estimated to be more than 100 μm using aerosol dynamics theories and the aforementioned viral loads.    
If respiratory particles (ie, particles emitted from respiratory tracts) are larger than the cutoff size between aerosols and droplets, they are categorised as droplets (ie, large earthbound respiratory particles), whereas if they are smaller than the cutoff size, they are catagorised as aerosol particles (ie, tiny airborne particles; appendix). The cutoff size between aerosols and droplets is highly dependent on the surrounding airflow conditions, including relative humidity and airflow velocity. The standard cutoff size between aerosols and droplets, which has been under debate in aerosol dynamics, ranges between 5 μm and 100 μm.  

DJ...droplets are "heavy" so 6 feet-2 meter distance of a patient offers "a lot of protection" (however contact of infected surfaces is a risk !) Aerosol spread is a higher risk...masks/eyeprotection needed !
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 03 Jul 2024 at 7:53am
DJ-The picture I am getting is;
-Mpox may spread via quite a lot of animals (not only the human one !)
-Virus-particles may spread as aerosols
-The idea Mpox is a "sex disease" is misleading-wrong ! 

DJ-Mpox can spread -like many other diseases- via sex...Most cases very likely do spread via infected surfaces...

By "promoting"Mpox as a "sex disease" people will be less willing to seek help when needed. They may ignore symptoms in pets...

Again; GOOD INFO !!!! Is essential ! (But sensationalism does sell...). 

Looking at the big "pandemic picture"...how far are we from burning witches, voodoo as a cure or other "magic"...?  Do we give a damn about science or are we going 100% stupid ? 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 05 Jul 2024 at 11:18pm
https://flutrackers.com/forum/forum/africa-ac/monkeypox/990497-south-africa-2024-mpox?view=stream or https://flutrackers.com/forum/forum/africa-ac/monkeypox/990497-south-africa-2024-mpox?view=stream latest (july 5) ;

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Source: https://www.sanews.gov.za/south-afri...ected-increase


Mpox cases rise to 20 with infections expected to increase
Friday, July 5, 2024

Four additional Mpox cases have been reported in KwaZulu-Natal and Gauteng, with infections expected to rise as contact tracing efforts are stepped up.

This pushes the total number of laboratory-confirmed cases of Mpox in South Africa to 20 since the outbreak in May 2024.

According to the Department of Health’s data, all cases involve males aged between 17 to 43 years old.

The recent infections include a 17-year-old man from Hillbrow in Johannesburg, a 37-year-old from Pretoria East, a 29-year-old from West Rand, and a 19-year-old from Durban in KwaZulu-Natal.

Of the 20 cases, 10 were recorded in Gauteng, nine cases in KwaZulu-Natal and one from Western Cape.

Meanwhile, the death toll has remained at three since the outbreak.​..

DJ See also https://www.facebook.com/photo.php?fbid=882473327245880&set=a.296257912534094&type=3&ref=embed_page or https://www.facebook.com/photo.php?fbid=882473327245880&set=a.296257912534094&type=3&ref=embed_page 

Very limited info on Mpox spread...So very likely the real situation in Africa may be worse...
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 06 Jul 2024 at 10:18am
https://flutrackers.com/forum/forum/africa-ac/monkeypox/984668-drc-mpox-monkeypox-outbreak-2024?view=stream or https://flutrackers.com/forum/forum/africa-ac/monkeypox/984668-drc-mpox-monkeypox-outbreak-2024?view=stream latest;

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South Kivu: 26 confirmed cases of Mpox reported in the Miti-Murhesa health zone

July 5, 2024

Bukavu, July 5, 2024 (ACP). – Twenty-six cases of monkeypox disease "Mpox" have been confirmed in the Miti-Murhesa health zone, 30 kilometers north of Bukavu in South Kivu in eastern Democratic Republic of Congo, a local health source said.

" To date, we already have sixty-nine cases (69) including (26) confirmed from all the samples that we sent to the INRB ," the head doctor of the Miti-Murhesa health zone, Doctor Serges Munyahu Cikuru, told the ACP on Friday.

" Almost all the health areas of our Miti-Murhesa health zone are affected by the disease, especially Kavumu, Mulungu-Miti, Kalwa and Murhesa ," added the Miti-Murhesa zone chief, specifying that the patients are being treated in medical facilities.

" The only message to the population is to ask them to respect hygiene standards to avoid contamination. This disease is very contagious and dangerous and is transmitted by direct contact ," said Serge Munyahu.

" The sudden onset of high fevers and skin rashes with lesions that can even spread all over the body and that are filled with fluids or pus and that end up drying out and forming scabs, these are the symptoms or signs that the suspected person or animal presents ," the source added.

The communications officer at the provincial health department, Doctor Claude Bahizire, said that currently twenty-two (22) out of the thirty-four (34) health zones in South Kivu are affected by monkeypox disease.

ACP/CL

Bukavu, 05 juillet 2024(ACP). -Vingt-six cas de maladie de la variole de singe « Mpox » ont été confirmés dans la zone de santé Miti-Murhesa, 30 kilomètres au nord de Bukavu au Sud-Kivu dans l’est de la République démocratique du Congo, a-t-on appris de source sanitaire locale.  « A ce…


DJ, https://en.wikipedia.org/wiki/Mpox_in_the_Democratic_Republic_of_the_Congo#2023-2024_outbreak or https://en.wikipedia.org/wiki/Mpox_in_the_Democratic_Republic_of_the_Congo#2023-2024_outbreak (last update may 25...)
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 10 Jul 2024 at 1:29am
While the NATO-west keeps pushing for endless wars-wasting trillions...destroying public healthcare in far too many countries...

https://www.thailandmedical.news/news/somnolence-and-shingles-seems-to-be-new-symptom-manifestation-of-covid-19-kp-3-and-lb-1-infections or https://www.thailandmedical.news/news/somnolence-and-shingles-seems-to-be-new-symptom-manifestation-of-covid-19-kp-3-and-lb-1-infections -just a reminder CoViD may cause skin problems...

https://www.mayoclinic.org/diseases-conditions/shingles/symptoms-causes/syc-20353054 or https://www.mayoclinic.org/diseases-conditions/shingles/symptoms-causes/syc-20353054 ; Shingles is a viral infection that causes a painful rash. Shingles can occur anywhere on your body. It typically looks like a single stripe of blisters that wraps around the left side or the right side of your torso.

Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox. After you've had chickenpox, the virus stays in your body for the rest of your life. Years later, the virus may reactivate as shingles.

Shingles isn't life-threatening. But it can be very painful.


DJ, CoViD may give old infections a new chance...

https://flutrackers.com/forum/forum/asia/all-other-diseases/monkeypox-ac/986360-taiwan-2024-mpox or https://flutrackers.com/forum/forum/asia/all-other-diseases/monkeypox-ac/986360-taiwan-2024-mpox ;

Source: https://news.tvbs.com.tw/english/2544956

Taiwan’s Mpox cases hit 377, CDC urges vaccination
Reporter TVBS News Staff
Release time:2024/07/09 14:18
Last update time:2024/07/09 14:30​

TAIPEI (TVBS News) — Taiwan has recorded 377 Mpox cases since the first imported case in June 2022, with 355 local and 22 imported cases, the Taiwan Centers for Disease Control (CDC) reported on Monday (July 8). Nantou County (南投£) confirmed four local cases among young Taiwanese men, who allegedly engaged in unprotected sex.

The global Mpox tally has reached over 98,000 cases. The Nantou County Public Health Bureau stated that Mpox has an incubation period of up to 21 days, and individuals can be contagious one to four days before symptoms appear. The bureau emphasized that vaccination remains the most effective prevention method.​..

DJ M-pox is very likely a GLOBAL problem ! A lot of spread may be via contact with contaminated surfaces...(doorhandles, taps, toiletseats...) NOT via sex !

The "sexualization" of Mpox makes it even harder to control !
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 12 Jul 2024 at 2:33am
https://www.thailandmedical.news/news/mpox-may-present-without-typical-skin-lesions-warns-doctor or https://www.thailandmedical.news/news/mpox-may-present-without-typical-skin-lesions-warns-doctor 

DJ; a few points;

-South Africa has another type/clade of Mpox then DRC/Congo

-HIV & Mpox=more severe disease

-Sex is part of the spread-but not all. Body fluids carry the virus-if a person has "open skin" and gets in contact with infected fluids it may spread

-DJ-CoViD can give skin symptoms...Mpox can give internal lesions...So it may get even easier to misinterpret diseases...

The Mpox spreading in parts of the globe may be different variants...(even more then the two earlier Congo/Central Africa and Nigeria/West Africa variants...)
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Dutch Josh Quote  Post ReplyReply Direct Link To This Post Posted: 14 Jul 2024 at 9:52am
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00187-6/fulltext#%20 or https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00187-6/fulltext#%20 ;

Mpox was previously thought to be a zoonotic disease endemic in parts of central, west, and east Africa; however, from 2022 to 2023, a large global outbreak of mpox from clade II monkeypox virus occurred, marking the first instance of sustained transmission outside of Africa since the first case of mpox in a human was identified in 1970. 
More recently, clade I monkeypox virus has been responsible for a growing outbreak in the Democratic Republic of the Congo, with evidence of sexual transmission suggesting the potential for global spread. 

The increasing burden of endemic African mpox, geographic expansion into previously unaffected areas, novel transmission via sexual contact, rising case fatality rates in rural areas, and transmission in urban areas raise serious health concerns, but African researchers still struggle to obtain funding to study this disease.
 The 2022–23 global mpox outbreak occurred despite repeated warnings from African researchers and calls for investment into diagnostic, therapeutic, and infection prevention tools. Swift public health responses and a notable increase in mpox research occurred almost entirely among high-income countries in Europe and North America. 
Given the substantial global reduction in mpox cases following the international response and the ongoing outbreaks and changing disease epidemiology in the Democratic Republic of the Congo, research to better understand mpox epidemiology, prevention, and treatment should be prioritised in Africa. 
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We have proposed the establishment of an African-led, multidisciplinary, multicountry Mpox Research Consortium (MpoxReC) in Africa with an overarching goal of establishing a research network to advance the elimination of mpox as a public health problem (with an initial focus on Cameroon, the Central African Republic, the Democratic Republic of the Congo, Ghana, Nigeria, and the Republic of the Congo). MpoxReC will integrate basic research; clinical studies; disease surveillance; risk communication; community engagement; phylogeographic, ecological, and anthropologic studies; novel studies for use of medical countermeasures; and capacity building to address mpox epidemics and ultimately eliminate its human-to-human transmission (appendix p 1). 

Names of principal investigators and collaborating institutions, organisations, and investigators are available in the appendix (pp 2–3). The MpoxReC regional research agenda was presented and endorsed at the first high-level international meeting on mpox in Kinshasa, the Democratic Republic of the Congo, in April, 2024.
DJ, Start with the source of the problem. Keeping countries poor means a lot of health crises...If you have one "doctor" per 100,000+ people forget about detection of health risks in time ! 

The latest mpox outbreaks in Africa require urgent collaborative efforts to address the evolving epidemiology and transmission dynamics of the disease. MpoxReC aims to establish a multidisciplinary research network to generate knowledge, strengthen surveillance, and enhance African public health responses.

DJ; Vaccines-at best-can be part of a solution ! Better education, surveilance, in time detection of diseases (not only Mpox) is needed. 

Besides that-why did Mpox "get a problem in the west" ? CoViD related ? 
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